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It is termed major aphthous ulceration (MaAU) or major recurrent aphthous stomatitis (MaRAS). Major aphthous ulcers (major aphthae) are similar to minor aphthous ulcers, but are more than 10 mm in diameter and the ulceration is deeper. [6] [7] Because the lesions are larger, healing takes longer (about twenty to thirty days), and may leave scars.
This disease is characterised by multifocal stenosing ulceration of the small intestine. The ulcers are circular or irregular in shape and their margins are always clear. The lesions involve only the mucosa and submucosa and are confined to the jejunum and proximal ileum. The intervening mucosa appears normal. Nonspecific inflammatory changes ...
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
Dogs are ten times more likely to be infected than humans. The disease in dogs can affect the eyes, brain, lungs, skin, or bones. [15] Histoplasmosis* is a fungal disease caused by Histoplasma capsulatum that affects both dogs and humans. The disease in dogs usually affects the lungs and small intestine. [16]
A malabsorption syndrome precipitated by the ingestion of foods containing gluten in a predisposed individual. It is characterized by inflammation of the small intestine, loss of microvilli structure, deficient nutrient absorption, and malnutrition. [4] Human immunodeficiency virus enteropathy
Slow down in peristalsis or movement of food through the small intestine (an increase in the transit time) to increase the time available for nutrient absorption [4] Osteoporosis is a very common comorbidity in people with short bowel syndrome who are on parenteral nutrition, with an estimated prevalence of 57-67%. [ 4 ]
Lower endoscopy to evaluate the rectum and distal large intestine (sigmoidoscopy) or entire colon and end of the small intestine (colonoscopy) for ulcers and inflammation; Although ulcerative colitis is a disease of unknown causation, inquiry should be made as to unusual factors believed to trigger the disease. [19]
Suspected causes include abnormal responses to bacteria or bacterial endotoxin, or a hypersensitivity to food. [2] Pathologically there is an increase in the permeability of the intestinal lining and a leakage of blood and proteins into the bowel. Clostridium perfringens has been found in large numbers in the intestines of many affected dogs. [1]