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The hair follicle is an organ found in mammalian skin. [ 1 ] It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. [ 1 ] This complex interaction induces the hair ...
The hair matrix, or simply matrix, produces the actual hair shaft as well as the inner and outer root sheaths of hair. [1] References This page was last edited ...
Encircling these cells is the matrix cell region, the hair follicle's proliferative compartment, responsible for the formation of different follicle compartments (except the ORS) and the production of crucial structural elements of hair - hair keratins and associated proteins known as KAPs. [1]
Matrix (biology) In biology, matrix (pl.: matrices) is the material (or tissue) in between a eukaryotic organism's cells. The structure of connective tissues is an extracellular matrix. Fingernails and toenails grow from matrices. It is found in various connective tissues.
In mammalian outer hair cells, the varying receptor potential is converted to active vibrations of the cell body. This mechanical response to electrical signals is termed somatic electromotility; [13] it drives variations in the cell's length, synchronized to the incoming sound signal, and provides mechanical amplification by feedback to the traveling wave.
Trichocyte (human) In mammals, trichocytes are the specialized epithelial cells from which the highly mechanically resilient tissues hair and nails are formed. They can be identified by the fact that they express "hard", "trichocyte" or "hair" keratin proteins. [1] These are modified keratins containing large amounts of the amino acid cysteine ...
Noggin, a known inhibitor of BMP4, is found within the matrix cells of the hair bulb. Other important factors to consider in the development of hair is the expression of Shh (sonic hedgehog), BMP7, BMP2, WNT, and β-catenin as these are required in early stage morphogenesis. [40] Other genes which can inhibit or interact with BMP4 are noggin ...
Anatomy of hair. The cortex of the hair shaft is located between the hair cuticle and medulla and is the thickest hair layer. It contains most of the hair's pigment, giving the hair its color. The major pigment in the cortex is melanin, which is also found in skin. The distribution of this pigment varies from animal to animal and person to person.