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The brain is a major target for the actions of alcohol, and heavy alcohol consumption has long been associated with brain damage. Studies clearly indicate that alcohol is neurotoxic, with direct effects on nerve cells. Chronic alcohol abusers are at additional risk for brain injury from related causes, such as poor nutrition, liver disease, and ...
Long-term, stable consequences of chronic hazardous alcohol use are thought to be due to stable alterations of gene expression resulting from epigenetic changes within particular regions of the brain. [26][27][28] For example, in rats exposed to alcohol for up to 5 days, there was an increase in histone 3 lysine 9 acetylation in the ...
Alcohol acts as a general central nervous system depressant, but it also affects some specific areas of the brain to a greater extent than others. Memory impairment caused by alcohol has been linked to the disruption of hippocampal function—particularly affecting gamma-Aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) neurotransmission which negatively impacts long-term potentiation ...
Using statistical methods based on genetic analyses, the authors of the study found that alcohol heightened dementia risk in proportion to the amount of alcohol consumed. This study contradicts ...
The study used 43,802 deaths linked to alcohol or tobacco but only 5475 other deaths as controls. [55] Competing causes of death might have confounded the results through a lack of data on other risk factors. For example, the study may have attributed a death to alcohol-related causes, even when a woman was diagnosed with terminal breast cancer ...
“Alcohol is used to help or try to regulate the nervous system when it’s used to soothe anxiety and depression, but we’re learning there are other ways to soothe our nervous system,” says ...
Alcohol kills 2.8 million people every year globally, causing cancer, ... It's probably because alcohol damages developing cells, said the senior editor of the study, Emma Allott, who teaches ...
Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation. This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [2]