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7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [ 1 ] [ 2 ] It is a non-selective antagonist of the adenosine receptors .
The characteristic signals, distinguishing theophylline from related methylxanthines, are approximately 3.23δ and 3.41δ, corresponding to the unique methylation possessed by theophylline. The remaining proton signal, at 8.01δ, corresponds to the proton on the imidazole ring, not transferred between the nitrogen.
Xanthine (/ ˈ z æ n θ iː n / or / ˈ z æ n θ aɪ n /, from Ancient Greek ξανθός xanthós ' yellow ' for its yellowish-white appearance; archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms. [2]
The man had sleep apnea—his airway was obstructed, which interrupted breathing at night, waking him repeatedly. ... One problem for Cooksey, often experienced by others, was a poorly fitting ...
Methylxanthines are chemical compounds which are derivatives of xanthine with one or more methyl groups, including: One methyl group: 1-Methylxanthine;
Most premature infants are affected by 'central' apnea due to the developmental stage of their respiratory tract. [2] Apnea of prematurity can increase the risk of chronic health conditions including retinopathy and increases the risk of problems with the infant's neurological development. Apnea lasting more than 60 seconds may result in death ...
Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor [20] which raises intracellular cAMP, activates PKA, inhibits TNF [21] [22] and leukotriene [23] synthesis, and reduces inflammation and innate immunity. [23]
8-Methoxymethyl-3-isobutyl-1-methylxanthine (MMPX) is a phosphodiesterase inhibitor. [1] References This page was last edited on 17 January ...