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The passage of large amounts of immunoglobulin light chains through the kidneys may cause inflammation or blockage of the kidney tubules. [2] The distal tubules of the kidneys secrete large amounts of uromucoid (Tamm–Horsfall protein). This is the dominant protein in normal urine and is thought to be important in preventing ascending urinary ...
The Dietary Inflammatory Index (DII) is a numerical score that assesses a diet for its effect on several biomarkers linked to inflammation. Its theoretical bounds are −8.87 to +7.98, and it is oriented such that negative scores are more anti-inflammatory and more positive scores are pro-inflammatory .
6037 503847 Ensembl ENSG00000169397 ENSMUSG00000050766 UniProt P12724 Q5GAN2 RefSeq (mRNA) NM_002935 NM_017389 RefSeq (protein) NP_002926 NP_059085 Location (UCSC) Chr 14: 20.89 – 20.89 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse Eosinophil cationic protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the ...
In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."
A new approach to a routine blood test could predict a person’s 30-year risk of heart disease, ... and an indicator of inflammation — are important predictors of a person's risk of heart ...
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
Gout is due to persistently elevated levels of uric acid (urate) in the blood (hyperuricemia). [ 2 ] [ 5 ] This occurs from a combination of diet, other health problems, and genetic factors. [ 1 ] [ 2 ] At high levels, uric acid crystallizes and the crystals deposit in joints, tendons , and surrounding tissues, resulting in an attack of gout. [ 1 ]
The Crohn's Disease Activity Index or CDAI is a research tool used to quantify the symptoms of patients with Crohn's disease.This is of useful importance in research studies done on medications used to treat Crohn's disease; most major studies on newer medications use the CDAI in order to define response or remission of disease.