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  2. Viagra may help prevent dementia by boosting brain blood flow

    www.aol.com/viagra-may-help-prevent-dementia...

    Every participant received 3-week regimens of sildenafil, placebo, and cilostazol — a treatment for vascular disease. Each course of drugs was separated by a “washout” period of at least 1 week.

  3. People who take Viagra have lower risk of Alzheimer’s: study

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  4. 5 major Alzheimer’s discoveries scientists made in 2024 - AOL

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    With an estimated 6.9 million Americans aged 65 and older currently living with Alzheimer's disease, the road to a cure seems long and uncertain.. But as the year comes to a close, experts are ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil was initially introduced for clinical trial in 1989. It was the result of extensive research on chemical agents targeting PDE5 that could be effective in treatment of coronary heart disease. [22] Sildenafil did not prove effective for coronary heart disease but an interesting side effect was discovered, a penile erection.

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