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Furthermore, anti-histone antibodies can also be positive in drug-induced lupus. [citation needed] Anti-Histone antibodies are positive in up to 95% of patients with drug induced lupus. The most common medications associated with drug induced lupus are hydralazine, procainamide, isoniazid, methyldopa, chlorpromazine, quinidine, and minocycline. [9]
Prolonged treatment may cause a syndrome similar to lupus, which can become fatal if the symptoms are not noticed and drug treatment stopped. [13] Hydralazine is within the top three drugs that is known to induce systemic lupus and this adverse drug event is dose dependent yet significant.
DR4 is associated with extraarticular [2] rheumatoid arthritis, [3] hydralazine-induced female systemic lupus erythematosus, [4] pemphigoid gestationis, [5] pemphigus foliaceus, [6] obstructive hypertrophic cardiomyopathy, [7] IgA nephropathy, [8] 'shared syndrome'-systemic sclerosis/rheumatoid arthritis [9] and polymyalgia rheumatica. [10]
So the classic presentation of lupus is fever, joint pain, and a rash in a woman of childbearing age, but the actual diagnosis is difficult because it can affect a variety of people of different genders and ages, and there’re also a wide variety of symptoms. There are general symptoms like fever and weight loss, as well as specific symptoms ...
Other medications used to treat lupus symptoms like depression, fatigue, and muscle pain may also cause weight gain as a side effect, Kirou adds. Or they may disrupt sleep by causing acid reflux ...
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [1]
Toni Braxton opened up about the long road to getting a lupus diagnosis, and why she didn’t initially go public about the autoimmune disease. “I worked hard to hide it for the longest time ...
Halsey announced in a June 5 Instagram post that she has lupus, an autoimmune disease which was diagnosed in 2022, and a rare white blood-cell disorder. In a prior post announcing the release of ...
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