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The underlying cause of this type of bronchoconstriction appear to be the large volume of cool, dry air inhaled during strenuous exercise. The condition appears to improve when the air inhaled is more fully humidified and closer to body temperature. This specific condition, in the general population, can vary between 7 and 20 percent.
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
Approximately 40% of children who experience a febrile seizure will have another one. [26] In those with epilepsy, fever can trigger a seizure. Additionally, in some, gastroenteritis, which causes vomiting and diarrhea, can lead to diminished absorption of anticonvulsants, thereby reducing protection against seizures. [27]
In children the short term use of steroids by mouth increases the risk of vomiting, behavioral changes, and sleeping problems. [41] Dysphonia: Inhaled corticosteroids are used for treatment of asthma as a standard treatment. This can cause local adverse effects like vocal cord dysfunction. [42]
Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8] Skin atrophy can occur with both prescription and over the counter steroids creams. [9] Low doses of prednisone by mouth can also result in skin atrophy.
[3] [8] The nasal spray is used for prevention and treatment of allergic rhinitis. [2] Nasal drops are used in the treatment of nasal polyps. The nasal spray can also be used in the mouth for mouth ulcers. [11] Fluticasone propionate in a topical form can be used to treat skin conditions such as eczema, psoriasis, and rashes. [17] [18]
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Wheezes can occasionally be heard without a stethoscope. The child may also experience apnea, or brief pauses in breathing, but this can occur due to many conditions that are not just bronchiolitis. After the acute illness, it is common for the airways to remain sensitive for several weeks, leading to recurrent cough and wheeze.
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