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Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic to be discovered. [6] It is primarily used to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.
Find out what typical and atypical antipsychotics are, what they are used for, how they work, and their potential risks and benefits.
The atypical antipsychotic clozapine has also been suggested as an alternative antipsychotic for patients experiencing tardive dyskinesia. [9] Tardive dyskinesia may reverse upon discontinuation of the offending agent or it may be irreversible, withdrawal may also make tardive dyskinesia more severe.
[120] [121] Typical antipsychotics and atypical risperidone can have a side effect of sexual dysfunction. [122] Clozapine, olanzapine, and quetiapine are associated with beneficial effects on sexual functioning helped by various psychotherapies.
AOL
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
The FDA's REMS program has been found to have unintentionally created barriers to accessing clozapine, a crucial antipsychotic drug for treatment-resistant schizophrenia, leading to tragic stories ...
Atypical antipsychotics include Amisulpride, Aripiprazole, Clozapine, Olanzapine, Paliperidone, and Quetiapine. [3] While both types of antipsychotic drugs are effective, the main differences are that atypical ones generally have fewer side effects compared to typical ones.