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Filgrastim, sold under the brand name Neupogen among others, is a medication used to treat low neutrophil count. [19] Low neutrophil counts may occur with HIV/AIDS, following chemotherapy or radiation poisoning, or be of an unknown cause. [19] It may also be used to increase white blood cells for gathering during leukapheresis. [19]
Trenbolone acetate also has the ability to increase red blood cell count. With a larger amount of red blood cells, blood oxygenation is enhanced. This allows for enhanced muscular endurance and therefore promotes a faster rate of recovery. Trenbolone acetate is capable of inhibiting glucocorticoids such as cortisol.
G-CSF when given early after exposure to radiation may improve white blood cell counts, and is stockpiled for use in radiation incidents. [24] [25] Mesoblast planned in 2004 to use G-CSF to treat heart degeneration by injecting it into the blood-stream, plus SDF (stromal cell-derived factor) directly to the heart. [26]
In humans treated with oprelvekin on a daily base a twofold increase in fibrinogen levels occurred. Healthy volunteers displayed an increase in von-Willebrand-factor (vWf) activity. Isolated molecules formed under oprelvekin were found to have exact the same multimere structure as the 'normal' factor and were therefore fully functioning.
Intramuscular injections are generally avoided in people with low platelet count or clotting problems, to prevent harm due to potential damage to blood vessels during the injection. They are also not recommended in people who are in hypovolemic shock , or have myopathy or muscle atrophy , as these conditions may alter the absorption of the ...
Granulocytes are most often collected through leukapheresis, a process that separates the donor's white blood cells from their red blood cells and plasma. Donors may be given corticosteroids or granulocyte colony-stimulating factor to increase their granulocyte count prior to the blood collection. Granulocytes have a short shelf life and it is ...
It is given by injection into a vein or by mouth. [3] Common side effects include nausea, diarrhea, fever, rash, shortness of breath, numbness, vision changes, and feeling tired. [3] Severe side effects include brain dysfunction, low blood cell counts, and lung inflammation. [3] Use in pregnancy will likely result in harm to the fetus. [3]
Unlike other blood products demand for platelet transfusions appears to be increasing in several countries around the world. [27] An ageing population, an increase in the number of people with blood cancer, and changes to the management of these cancers are likely the major reasons for the rise in demand for platelets. [27]
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