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Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.
Allopurinol is a medication used to decrease high blood uric acid levels. [5] It is specifically used to prevent gout , prevent specific types of kidney stones and for the high uric acid levels that can occur with chemotherapy .
In the UK, NICE has found that febuxostat has a higher cost/benefit ratio than allopurinol and on that basis recommended febuxostat as a second-line drug for people who cannot use allopurinol. [12] In 2010, before it became generic in the United States, it cost about US$160 per month as opposed to allopurinol which was about $14 per month. [31]
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Lesinurad/allopurinol (trade name Duzallo) is a fixed-dose combination drug for the treatment of gout. [1] It contains 200 mg of lesinurad and 300 mg of allopurinol.In August 2017, the US Food and Drug Administration approved it for the treatment of hyperuricemia associated with gout in patients for whom target serum uric acid levels have not been achieved with allopurinol alone. [2]
A Tennessee judge will end former NFL star Michael Oher’s conservatorship agreement with Sean and Leigh Anne Touhy, after he filed a lawsuit claiming he had been misled to believe he had been ...
A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]
Raising kids is rewarding, but let's be honest—it's expensive. The average cost to raise a child until age 18? According to Northwestern Mutual, it's a whopping $300,000, as Business Insider ...