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When mold spores are inhaled by an immunocompromised individual, some mold spores may begin to grow on living tissue, [28] attaching to cells along the respiratory tract and causing further problems. [29] [30] Generally, when this occurs, the illness is an epiphenomenon and not the primary pathology. Also, mold may produce mycotoxins, either ...
Normally the mucociliary clearance mechanism of the airways of the lungs removes inhaled particles. However, in those with underlying lung diseases, such as cystic fibrosis or bronchiectasis, this mucociliary clearance mechanism is impaired and aspergillus spores (which are 2-5 μm in diameter) are able to colonize the airways and sinuses. [13]
This can lead to treatment being delayed or unsought altogether. [3] In a very small portion of people, fungal pneumonia can lead to chronic pneumonia, fungemia (presence of fungi in the blood), meningitis (infection of the meninges of the brain or spine), or even death. However, this is extremely rare and the vast majority of cases go ...
The most common organ affected by aspergilloma is the lung. Aspergilloma mainly affects people with underlying cavitary lung disease such as tuberculosis, sarcoidosis, bronchiectasis, cystic fibrosis and systemic immunodeficiency. Aspergillus fumigatus, the most common causative species, is typically inhaled as small (2 to 3 micron) spores.
Mold allergies are present in a minority of the population that is genetically predisposed to mold, and usually this allergy is not life threatening. Black molds, or so called toxic molds, can ...
A. fumigatus is responsible for a spectrum of lung diseases known as aspergilloses. [4] ABPA causes airway inflammation, leading to bronchiectasis—a condition marked by abnormal dilation of the airways. Left untreated, the immune system and fungal spores can damage sensitive lung tissues and lead to scarring. [5]
C. immitis is dormant during long dry spells, then develops as a mold with long filaments that break off into airborne spores when it rains. The spores, known as arthroconidia, are swept into the air by disruption of the soil, such as during construction, farming, low-wind or singular dust events, or an earthquake.
In cases of sporotrichosis affecting the lungs, the fungal spores enter by inhalation. [1] Sporotrichosis can be acquired by handling cats with the disease; it is an occupational hazard for veterinarians. [1] Treatment depends on the site and extent of infection. [1] Topical antifungals may be applied to skin lesions. [1]
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