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Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.
Lupus nephritis: Kidneys: Anti-dsDNA, Anti-Sm, Anti-nuclear antibodies Confirmed Up to 60% of those with Lupus [49] Interstitial nephritis: Kidneys: Various autoantibodies Probable Varies widely, often drug-induced [50] Interstitial cystitis: Bladder: Anti-urothelial and anti-nuclear antibodies Probable 100-450 per 100,000 women, less common in ...
The NHS says lupus, or systemic lupus erythematosus, is a long-term condition that subverts the immune system, causing the body’s natural defence measures to turn on healthy organs. There is ...
The disease impacts about 1.5 million Americans, but women are nine times more likely to develop lupus than men. And the cause of lupus has largely remained a mystery—until now. ... and symptoms ...
These deposits and inflammation seem to be the cause of most of the symptoms of lupus, which remember is a type III hypersensitivity reaction. Many patients, though, also develop antibodies targeting other cells like red and white blood cells, and molecules like various phospholipids, which can mark them for phagocytosis and destruction ...
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