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Milk sickness, also known as tremetol vomiting or, in animals, as trembles, is a kind of poisoning, characterized by trembling, vomiting, and severe intestinal pain, that affects individuals who ingest milk, other dairy products, or meat from a cow that has fed on white snakeroot plant, which contains the poison tremetol.
Tremetol, an oil with a straw-colored tinge, was first isolated from white snakeroot by J.F. Couch in 1929. Column chromatography of tremetol yielded a hydrocarbon, two steroids, and three ketones. Further isolation experiments revealed that tremetone is the major ketone constituent of the compound tremetol.
Ageratina altissima, also known as white snakeroot, [3] richweed, [3] or white sanicle, [4] is a poisonous perennial herb in the family Asteraceae, native to eastern and central North America. An older binomial name for this species is Eupatorium rugosum , but the genus Eupatorium has undergone taxonomic revision by botanists , and some species ...
The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
Heterakis gallinarum is a nematode parasite that lives in the cecum of some galliform birds, particularly in ground feeders such as domestic chickens and turkeys. It causes infection that is mildly pathogenic. However, it often carries a protozoan parasite Histomonas meleagridis which causes of histomoniasis (blackhead disease).
Bixby discovered that white snakeroot (Ageratina altissima) was the cause of milk sickness from grazing cows eating the wild plant which fatally poisoned the milk consumed by frontier settlers Anna Pierce Hobbs Bixby , sometimes spelled Bigsby , born Anna Pierce ( c. 1810 – c. 1870), was a midwife , frontier doctor , dentist , herbologist ...
A large animal reservoir is present as well, with up to 100% of poultry, including chickens, turkeys, and waterfowl, having asymptomatic infections in their intestinal tracts. Infected chicken feces may contain up to 10 9 bacteria per 25 grams, and due to the animals' close proximity, the bacteria are rapidly spread to other chickens. This ...
Dogs and pigs are occasionally poisoned with this compound while ruminants are resistant. [27] But when the exposure of this compound in dogs is quite long they may have gastric irritation and respiratory difficulties. Death can then be followed within 6–48 hours depending on the quantity of ANTU ingested.
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