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Verrucotoxin (VTX) is a lethal venom produced by the dorsal fins of Synanceia verrucosa. This species of reef stonefish is connected to the family Synanceiidae. The venom of this species of stonefish is a tetrameric glycoprotein with cardiovascular and cytolytic effects. [1]
Synanceia is a genus of ray-finned fish belonging to the subfamily Synanceiinae, the stonefish, which is classified within the family Scorpaenidae, the scorpionfish and relatives. Stonefish are the most venomous fish known; stings can be fatal to humans.
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Synanceia verrucosa are usually brown or grey, and may have areas of yellow, orange, or red. [8] The dorsal fin contains between 12 and 14 spines and 5 and 7 soft rays while the anal fin has 3 spines and 5 or 6 soft rays. [2] The dorsal spines are of equal length with a thicker sheath of skin containing the venom glands at their base.
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Synanceia horrida is, like other stonefishes, regarded as one of the most dangerous venomous fishes. Each fin spine has a fleshy cover at its base where there are two venom-producing glands. When the fish is disturbed, it erects its spines; if the fish is stepped on, the spines act like hypodermic syringes, injecting venom into the wounds.