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The CSF/serum glucose ratio, also known as CSF/blood glucose ratio, is a measurement used to compare CSF glucose and blood sugar. Because many bacteria metabolize glucose, and because the blood–brain barrier minimizes transversal, the ratio can be useful in determining whether there is a bacterial infection in the CSF. The normal ratio is 0.6 ...
CSF glucose levels can be useful in distinguishing among causes of meningitis as more than 50% of patients with bacterial meningitis have decreased CSF glucose levels while patients with viral meningitis usually have normal CSF glucose levels. Decrease in glucose levels during a CNS infection is caused due to glycolysis by both white cells and ...
Reference ranges for other molecules in CSF Substance Lower limit Upper limit Unit Corresponds to % of that in plasma Glucose: 50 [2] 80 [2] mg/dL ~60% [1] 2.2, [3] 2.8 [1] 3.9, [3] 4.4 [1] mmol/L Protein: 15 [1] [2] 40, [4] 45 [1] [2] mg/dL ~1% [1] Albumin: 7.8 [5] 40 [5] mg/dL: 0 [6] - 0.7% [6] - corresponding to an albumin (CSF/serum ...
Historically, blood glucose values were given in terms of whole blood, but most laboratories now measure and report plasma or serum glucose levels. Because red blood cells (erythrocytes) have a higher concentration of protein (e.g., hemoglobin) than serum, serum has a higher water content and consequently more dissolved glucose than does whole ...
In bacterial meningitis it is typically lower; the CSF glucose level is therefore divided by the blood glucose (CSF glucose to serum glucose ratio). A ratio ≤0.4 is indicative of bacterial meningitis; [52] in the newborn, glucose levels in CSF are normally higher, and a ratio below 0.6 (60%) is therefore considered abnormal. [8]
After all, glucose is the brain’s primary fuel. Skipping breakfast might also have some long-term negative consequences on brain health, according to a study released on November 30, 2024, in ...
The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.
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