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Brodmann areas have been discussed, debated, refined, and renamed exhaustively for nearly a century and remain the most widely known and frequently cited cytoarchitectural organization of the human cortex. Many of the areas Brodmann defined based solely on their neuronal organization have since been correlated closely to diverse cortical functions.
The cell cortex, also known as the actin cortex, cortical cytoskeleton or actomyosin cortex, is a specialized layer of cytoplasmic proteins on the inner face of the cell membrane. It functions as a modulator of membrane behavior and cell surface properties.
The cerebral cortex, also known as the cerebral mantle, [1] is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals.It is the largest site of neural integration in the central nervous system, [2] and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness.
The mammalian cerebral cortex, the grey matter encapsulating the white matter, is composed of layers. The human cortex is between 2 and 3 mm thick. [11] The number of layers is the same in most mammals, but varies throughout the cortex. 6 layers can be recognized in the neocortex, although many regions lack one or more layers.
The human cerebral cortex divided into Brodmann areas on the basis of cytoarchitecture.. Cytoarchitecture (from Greek κύτος 'cell' and ἀρχιτεκτονική 'architecture'), also known as cytoarchitectonics, is the study of the cellular composition of the central nervous system's tissues under the microscope.
In humans, the cerebral cortex contains approximately 14–16 billion neurons, [1] and the estimated number of neurons in the cerebellum is 55–70 billion. [2] Each neuron is connected by synapses to several thousand other neurons, typically communicating with one another via cytoplasmic processes known as dendrites and axons.
Donald Hebb theoretically developed the concept of neuronal ensemble in his famous book "The Organization of Behavior" (1949). He defined "cell assembly" as "a diffuse structure comprising cells in the cortex and diencephalon, capable of acting briefly as a closed system, delivering facilitation to other such systems". Hebb suggested that ...
Betz cells are the largest cells (by size of cell body) in the nervous system. [40] The adult human brain is estimated to contain 86±8 billion neurons, with a roughly equal number (85±10 billion) of non-neuronal cells. [41] Out of these neurons, 16 billion (19%) are located in the cerebral cortex, and 69 billion (80%) are in the cerebellum ...