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The treatment is a combination of systemic antibiotics, debridement of infectious and necrotic tissue and local antibiotics applied to the joint space. The bacteria that usually cause prosthetic joint infections commonly form a biofilm , or a thick slime that is adherent to the artificial joint surface, thus making treatment challenging.
Depending on the type of surgery and anticipated contamination associated with it, combinations of different agents or different routes of administration (e.g. intravenous and oral antibiotics) might be beneficial in reducing perioperative adverse events. [6] [7] For prophylaxis in surgery, only antibiotics with good tolerability should be used.
In case of gut involvement also fungi may play a role. For patients unable to undergo major surgery, the outcome of conservative approach remains uncertain but usually provides for life-long suppressive antibiotic therapy. In selected cases an attempt of stopping antibiotic treatment after 3-6 months can be done. [20]
The patient is allowed to go home the same day and the recovery time is anywhere from two weeks to two months barring any complications such as infection. As a follow-up, a physician may prescribe an oral or topical antibiotic or a special soak to be used for about a week after the surgery. Some use "lateral onychoplasty," or "wedge resection ...
With the dizzying pace of the past 14 months, being incapacitated for even a few hours can be risky. ... The infection was treated successfully with antibiotics, but doctors said the surgery was ...
Children with acute otitis media who are younger than six months of age are generally treated with amoxicillin or other antibiotics. Although most children with acute otitis media who are older than two years old do not benefit from treatment with amoxicillin or other antibiotics, such treatment may be helpful in children younger than two years old with acute otitis media that is bilateral or ...
There has been significant recent trial evidence that uncomplicated appendicitis can be treated with either antibiotics or appendicectomy, [4] [5] with 51% of those treated with antibiotics avoiding an appendectomy after 3 years. [6] After appendicectomy the main difference in treatment is the length of time the antibiotics are administered.
The antibiotic treatment may select for bacterial strains with physiologically or genetically enhanced capacity to survive high doses of antibiotics. Under certain conditions, it may result in preferential growth of resistant bacteria, while growth of susceptible bacteria is inhibited by the drug. [ 84 ]