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Progesterone (P4), sold under the brand name Prometrium among others, is a medication and naturally occurring steroid hormone. [20] It is a progestogen and is used in combination with estrogens mainly in hormone therapy for menopausal symptoms and low sex hormone levels in women.
[50] [51] Reviews from before 1980 reported a high incidence of adverse mood effects with combined birth control pills. [48] However, doses of estrogens and progestogens in birth control pills before 1980 were considerably higher than those used today, and these doses frequently caused unpleasant side effects that may have unfavorably ...
Side effects of dienogest include menstrual irregularities, headaches, nausea, breast tenderness, depression, and acne, among others. [14] Dienogest is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like progesterone .
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Progesterone is used as part of hormone replacement therapy in people who have low progesterone levels, and for other reasons. For purposes of comparison with normal physiological circumstances, luteal phase levels of progesterone are 4 to 30 ng/mL, while follicular phase levels of progesterone are 0.02 to 0.9 ng/mL, menopausal levels are 0.03 to 0.3 ng/mL, and levels of progesterone in men ...
Different sources note different incidence of side effects. The most common side effect is breakthrough bleeding. Combined oral contraceptive pills can improve conditions such as dysmenorrhea, premenstrual syndrome, and acne, [105] reduce symptoms of endometriosis and polycystic ovary syndrome, and decrease the risk of anemia. [106]
More serious side effects include bone loss, blood clots, allergic reactions, and liver problems. [10] Use is not recommended during pregnancy as it may harm the baby . [ 10 ] MPA is an artificial progestogen , and as such activates the progesterone receptor , the biological target of progesterone . [ 4 ]
Norgestrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. [6] It has weak androgenic activity and no other important hormonal activity. [6] Norgestrel was patented in 1961 and came into medical use, specifically in birth control pills, in ...
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