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Antidepressant discontinuation syndrome is a relatively new phenomenon, being identified and described from 1950s onwards, in parallel with discovery and introduction of modern antidepressant medications, with the first MAOIs, and TCAs introduced from the 1950s onwards and the first SSRIs from the 1980s onwards. [8]
Though there may be times you want to stop taking your medication, abruptly stopping SSRI treatment can result in antidepressant discontinuation syndrome, with symptoms like insomnia, mood ...
Typically, brain zaps are associated with antidepressant discontinuation syndrome (ADS), which impacts an estimated 20 percent of people who abruptly stop or reduce their use of medication.
Cases have reported persisting chronic symptoms, [75] and antidepressant discontinuation may contribute to ongoing features. [76] Following appropriate medical management, SS is generally associated with a favorable prognosis.
It is considered a distinct phenomenon from antidepressant discontinuation syndrome, post-acute withdrawal syndrome, and major depressive disorder, [70] [68] and should be distinguished from sexual dysfunction associated with depression [70] and persistent genital arousal disorder. [64]
Impact of antidepressant discontinuation syndrome Joao L. de Quevedo, MD, PhD , a psychiatrist at UTHealth Houston, not involved in this research, spoke to Medical News Today about its findings.
As with SSRIs, the abrupt discontinuation of an SNRI usually leads to withdrawal, or "discontinuation syndrome", which could include states of anxiety and other symptoms. Therefore, it is recommended that users seeking to discontinue an SNRI slowly taper the dose under the supervision of a professional.
Serotonin syndrome. Irritability. Flu-like symptoms. ... Changing your dosage or abruptly stopping your medication could cause you to experience antidepressant withdrawal symptoms like those ...