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HPV types 16 and 18 are the cause of 75% of cervical cancer cases globally, while 31 and 45 are the causes of another 10%. [ 45 ] Women who have multiple sexual partners, or have partners who have multiple sexual partners, regardless of sex are at higher risk of cervical cancer.
Certain cancers can be prevented with vaccines against the viruses that cause them (e.g., HPV vaccines as prevention against cervical cancer). [9] Additionally, patient education about worrisome symptoms that require further evaluation is paramount to reduce morbidity and mortality from cancer.
All HPV vaccines protect against at least HPV types 16 and 18, which cause the greatest risk of cervical cancer. The quadrivalent vaccines also protect against HPV types 6 and 11. The nonavalent vaccine Gardasil 9 provides protection against those four types (6, 11, 16, and 18), along with five other high-risk HPV types responsible for 20% of ...
Early detection can be life-saving.
Cervical cancer is caused by HPV (human papillomavirus), which is the most common sexually transmitted infection in the U.S., according to the Centers for Disease Control and Prevention (CDC).
By contrast, HPV types 6 and 11 are considered low risk because they’re not associated with cancer, but they can cause genital warts. HPV spreads through sexual contact, including direct genital ...
Human Papilloma Virus (HPV) is a common sexually transmitted disease that has been associated with some gynecologic cancers, including those of the cervix, vagina, and vulva. [20] A clear link between human papilloma virus and cervical cancer has long been established, with HPV associated with 70% to 90% of cases. [21]
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.