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FACIT collagen is found in various tissue areas to modulate the surface properties of collagen fibrils and generate tissue-specific three-dimensional patterns in the extracellular matrix. [3] For example, collagen XIV connects the fibrillar networks of the cartilage and skin, [ 3 ] and XII is found in connective tissues, particularly at the ...
A better understanding of the mechanisms of collagen fibrillogenesis as well as an understanding of the regulators of the process would allow for a better understanding of diseases that affect collagen fibril formation and assembly such as Ehlers-Danlos syndromes (EDS). On a broader spectrum, an understanding of the processes that lie behind ...
Collagen alpha-2(V) chain is a protein that in humans is encoded by the COL5A2 gene. [5] [6] This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains.
107581 Ensembl ENSG00000084636 ENSMUSG00000040690 UniProt Q07092 Q8BLX7 RefSeq (mRNA) NM_001856 NM_028266 RefSeq (protein) NP_001847 NP_082542 NP_001391281 NP_001391282 Location (UCSC) Chr 1: 31.65 – 31.7 Mb Chr 4: 129.94 – 129.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen alpha-1(XVI) chain is a protein that in humans is encoded by the COL16A1 gene. Function This ...
Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. [3] In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and accounts for 6% of the weight to skeletal muscle. [4] The fibroblast is the most common cell creating collagen in ...
Collagen alpha-3(VI) chain is a protein that in humans is encoded by the COL6A3 gene. [ 5 ] [ 6 ] [ 7 ] This protein is an alpha chain of type VI collagen that aids in microfibril formation. [ 8 ] As part of type VI collagen, this protein has been implicated in Bethlem myopathy, Ullrich congenital muscular dystrophy (UCMD), and other diseases ...
Linearized PDF files (also called "optimized" or "web optimized" PDF files) are constructed in a manner that enables them to be read in a Web browser plugin without waiting for the entire file to download, since all objects required for the first page to display are optimally organized at the start of the file. [26]
C. C-terminal telopeptide; Collagen, type XI, alpha 2; Type IV collagen; Collagen VI; Collagen-induced arthritis; Collagen, type I, alpha 2; Collagen, type III, alpha 1