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209448 Ensembl ENSG00000180818 ENSMUSG00000022484 UniProt Q9NYD6 P31257 RefSeq (mRNA) NM_017409 NM_010462 RefSeq (protein) NP_059105 NP_034592 Location (UCSC) Chr 12: 53.99 – 53.99 Mb Chr 15: 102.88 – 102.88 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C10 is a protein that in humans is encoded by the HOXC10 gene. Function This gene belongs to the homeobox ...
Six Hox genes are dispersed in the genome of Caenorhabditis elegans, a roundworm. [10]: fig. 3 Hydra and Nematostella vectensis, both in the phylum Cnidaria, have a few Hox/ParaHox-like homeobox genes. [55] [11] Hox gene expression has also been studied in brachiopods, [56] annelids, [57] and a suite of molluscs. [58]
Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. [ 5 ] [ 6 ] [ 7 ] Hox-C6 expression is highest in the fallopian tube and ovary. [ 8 ] HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.
The mir-10 gene is located near to the HoxB1a and HoxB3a genes within the zebrafish genome, Hox-1 and Hox-3 paralogues located on different Hox clusters are not targets of miR-10. [19] Human HOXD10 gene has also been shown experimentally to be repressed by miR-10a and miR-10b. [9] [20] [21]
The Cdx protein family is a group of the transcription factor proteins which bind to DNA to regulate the expression of genes. [1] In particular this family of proteins can regulate the Hox genes . They are regulators of embryonic development and hematopoiesis in vertebrates, and are also involved in the development of some types of ...
15424 Ensembl ENSG00000172789 ENSMUSG00000022485 UniProt Q00444 P32043 RefSeq (mRNA) NM_018953 NM_175730 RefSeq (protein) NP_061826 NP_783857 Location (UCSC) Chr 12: 54.03 – 54.04 Mb Chr 15: 102.88 – 102.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene. Function This gene belongs to the homeobox ...
The HOX gene contains four clusters (A, B, C, and D). The sense strand of the HOXA gene codes for proteins. Alternative names for HOXA11-AS lncRNA are: HOXA-AS5, HOXA11S, HOXA11-AS1, HOXA11AS, or NCRNA00076. This gene is 3,885 nucleotides long and resides at chromosome 7 (7p15.2) and is transcribed from an independent gene promoter.
Robb Krumlauf is an American developmental biologist.He is best known for researching the Hox family of transcription factors.He is most interested in understanding the role of the Hox genes in the hindbrain and their role in areas of animal development, such as craniofacial development.