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  2. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender ...

  3. 5α-Pregnan-17α-ol-3,20-dione - Wikipedia

    en.wikipedia.org/wiki/5α-Pregnan-17α-ol-3,20-dione

    The androgen backdoor pathway (red arrows) roundabout testosterone embedded in within conventional androgen synthesis that lead to 5α-dihydrotestosterone through testosterone. [7] [8] [9] 5α-Pregnan-17α-ol-3,20-dione (17-OH-DHP) is a progestogen, i.e., it binds to the progesterone receptors.

  4. Dihydrotestosterone - Wikipedia

    en.wikipedia.org/wiki/Dihydrotestosterone

    Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition.

  5. Here's Why Testosterone Is a Female Hormone, Too - AOL

    www.aol.com/heres-why-testosterone-female...

    Research on women and testosterone has been limited, but as more is done, experts are seeing that the hormone affects the female sex drive, just as it does the male. It also plays an essential ...

  6. Androgen backdoor pathway - Wikipedia

    en.wikipedia.org/wiki/Androgen_backdoor_pathway

    In contrast, in the canonical pathway, 5α-reductase targets the 4,5-double bond in testosterone, producing dihydrotestosterone directly. The backdoor pathway was initially described as a biosynthetic route where 5α-reduction of 17α-hydroxyprogesterone ultimately leads to dihydrotestosterone. Since then, several other pathways have been ...

  7. Androstanolone - Wikipedia

    en.wikipedia.org/wiki/Androstanolone

    Androstanolone, or stanolone, also known as dihydrotestosterone (DHT) and sold under the brand name Andractim among others, is an androgen and anabolic steroid (AAS) medication and hormone which is used mainly in the treatment of low testosterone levels in men. [2]

  8. Androgen - Wikipedia

    en.wikipedia.org/wiki/Androgen

    To further test the role of activated androgen receptors on AHN, flutamide, an antiandrogen drug that competes with testosterone and dihydrotestosterone for androgen receptors, and dihydrotestosterone were administered to normal male rats. Dihydrotestosterone increased the number of BrdU cells, while flutamide inhibited these cells.

  9. Prenatal hormones and sexual orientation - Wikipedia

    en.wikipedia.org/wiki/Prenatal_hormones_and...

    If SRY exists, then the gonads develop as testes, and commence the production of androgen hormones, mainly testosterone, dihydrotestosterone (DHT) and androstenedione; production of testosterone and conversion into dihydrotestosterone during weeks 6 to 12 of pregnancy are key factors in the production of a male fetus's penis, scrotum and ...