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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
The development of selective 5-HT 3 receptor antagonists was a dramatic improvement in the treatment of nausea and vomiting. [30] Ondansetron, granisetron, dolasetron and palonosetron are currently approved in the United States, and form the cornerstone of therapy for the control of acute emesis with chemotherapy agents with moderate to high ...
Nausea and vomiting can be extremely distressing for patients, and so is one of their major concerns. [10] Vomiting has been associated with major complications, such as pulmonary aspiration of gastric content, and might endanger surgical outcomes after certain procedures, for example after maxillofacial surgery with wired jaws.
“Zofran is an anti-nausea medication,” says Qing, and it’s typically used preventatively. Zofran is an antiemetic that works by blocking the chemical that causes nausea and vomiting, per the ...
Midazolam (Versed) is given at the onset of anesthesia and has been shown in recent trials to be as effective as ondansetron, but most effective when used in combination with ondansetron. [15] Lorazepam (Ativan) is said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine. [citation needed]
Nausea can be caused by weight loss drugs, pregnancy, food poisoning, migraines. Doctors share home remedies for nausea, including ginger and peppermint.
These drugs block one or more of the nerve signals that cause nausea and vomiting. During the first 24 hours after chemotherapy, the most effective approach appears to be blocking the 5-HT 3 nerve signal. [10] Approved 5-HT 3 inhibitors include dolasetron (Anzemet), granisetron (Kytril, Sancuso), and ondansetron (Zofran). Their antiemetic ...
2. Eat Smaller, More Frequent Meals. Instead of three main meals, try eating smaller, more frequent meals throughout the day. This can help if nausea is making it hard to feel like eating or if ...
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