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  2. Lupus nephritis - Wikipedia

    en.wikipedia.org/wiki/Lupus_nephritis

    The proliferative forms of lupus nephritis are associated with a higher risk of progression to end stage kidney disease. [21] Black and Hispanic people with lupus nephritis are more likely to present with severe disease at initial presentation (with more proteinuria and more extensive histopathologic changes) and progress to end stage kidney ...

  3. Voclosporin - Wikipedia

    en.wikipedia.org/wiki/Voclosporin

    Lupus nephritis commonly leads patients to chronic kidney failure and therefore places an emphasis on early intervention for improving treatment outcomes. It is a significant risk factor for morbidity and mortality in systemic lupus erythematosus. The management of lupus nephritis comprises immunosuppressive therapy to lessen inflammation and ...

  4. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]

  5. Belimumab - Wikipedia

    en.wikipedia.org/wiki/Belimumab

    Belimumab is primarily used in people with systemic lupus erythematosus. When it was introduced in 2011, it was the first new drug approved to treat lupus in 56 years. [8] Sales rose to $31.2 million in the first quarter of 2012. [37] The total cost for the first year of treatment with belimumab is $28,000. [38]

  6. List of autoimmune diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_autoimmune_diseases

    Lupus nephritis: Kidneys: Anti-dsDNA, Anti-Sm, Anti-nuclear antibodies Confirmed Up to 60% of those with Lupus [49] Interstitial nephritis: Kidneys: Various autoantibodies Probable Varies widely, often drug-induced [50] Interstitial cystitis: Bladder: Anti-urothelial and anti-nuclear antibodies Probable 100-450 per 100,000 women, less common in ...

  7. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    There is no cure for Lupus. The treatment of SLE involves preventing flares and reducing their severity and duration when they occur. [118] Treatment can include corticosteroids and anti-malarial drugs. Certain types of lupus nephritis such as diffuse proliferative glomerulonephritis require intermittent cytotoxic drugs.

  8. Diffuse proliferative nephritis - Wikipedia

    en.wikipedia.org/.../Diffuse_proliferative_nephritis

    The cause of diffuse proliferative glomerulonephritis (DPGN) depends on the severity of the disease. DPGN is a secondary disease, in that a disease that a patient already has causes DPGN to occur. The most common associated disease of DPGN is severe systemic lupus erythematosus(SLE). [4] Specifically, Lupus nephritis class IV. [5]

  9. Liz Lightstone - Wikipedia

    en.wikipedia.org/wiki/Liz_Lightstone

    Alongside development new treatment strategies, Lightstone searched for urine biomarkers that could be indicative of the outcome of lupus nephritis. [10] Lighthouse has written the clinical guidelines on the management of lupus nephritis in adults and the management of pregnancy in women with lupus. [11]

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