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The term "NK T cells" was first used in mice to define a subset of T cells that expressed the natural killer (NK) cell-associated marker NK1.1 (CD161). It is now generally accepted that the term "NKT cells" refers to CD1d-restricted T cells , present in mice and humans, some of which coexpress a heavily biased, semi-invariant T-cell receptor ...
Natural killer cells, also known as NK cells, are a type of cytotoxic lymphocyte critical to the innate immune system.They are a kind of large granular lymphocytes [1] [2] (LGL), and belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. [3]
Group 2 CD1 molecules activate a group of T cells, known as Natural killer T cells because of their expression of NK surface markers such as CD161. Natural Killer T (NKT) cells are activated by CD1d-presented antigens, and rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production.
Natural killer T cells ... Markers of T cell activation include CD69, CD71 and CD25 (also a marker for Treg cells), and HLA-DR (a marker of human T cell activation ...
Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.. A cytotoxic T cell (also known as T C, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8 + T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens such as viruses or bacteria, or ...
T-cell surface glycoprotein CD1d encoded by the CD1D gene. CD1d-presented lipid antigens activate a special class of T cells, known as natural killer T cells, through the interaction with the T-cell receptor present on NKT membranes CD1e: T-cell surface glycoprotein CD1e is a protein in humans encoded by the CD1E gene. CD2
CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, macrophages, and certain T cells. [1] [2] CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. [3]
CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms.
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related to: natural killer t cells marker