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The syndrome presents with hematuria (blood in the urine) and flank (a region of the lower back beneath the ribs and above the ilium) pain which can result from a number of causes. Nonglomerular causes of bleeding (e.g., urinary infection, tumor, or nephrolithiasis) must be excluded.
Thin basement membrane disease must be differentiated from the other two common causes of glomerular hematuria, IgA nephropathy and Alport syndrome. The history and presentation are helpful in this regard: [citation needed] In Alport syndrome, there is often a family history of kidney failure, which may be associated with hearing impairment.
Purpura, arthritis, and abdominal pain are known as the "classic triad" of Henoch–Schönlein purpura. [5] Purpura occur in all cases, joint pains and arthritis in 80%, and abdominal pain in 62%. Some include gastrointestinal hemorrhage as a fourth criterion; this occurs in 33% of cases, sometimes, but not necessarily always, due to ...
A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
Generally, diseases outlined within the ICD-10 codes N00-N39 within Chapter XIV: Diseases of the genitourinary system should be included in this category. Articles relating to urologic diseases , including urinary tract infections , kidney stones , bladder control problems, and prostate problems, among others.
Joint pain [9] [10] Muscle pain [11] Itching [11] Bone deformation; Bone fracture [12] The broader concept of chronic kidney disease-mineral and bone disorder (CKD-MBD) [1] is not only associated with fractures but also with cardiovascular calcification, poor quality of life and increased morbidity and mortality in CKD patients (the so-called ...
The clinical presentation of AIP is highly variable and non-specific. The patients are typically asymptomatic, with most gene carriers having no family history because the condition had remained latent for several generations. The syndrome marked by acute attacks affects only 10% of gene carriers. [4] The mean age at diagnosis is 33 years old. [5]
In some, the x-ray findings may correspond to symptoms of back stiffness with flexion/extension or with mild back pain. [2] Back pain or stiffness may be worse in the morning. [4] Rarely, large anterior cervical spine osteophytes may affect the esophagus or the larynx and cause pain, difficulty swallowing [5] [6] or even dyspnea. [7]