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Paroxysmal symptoms include tonic, tonic–clonic, or myoclonic limb movements, [8] dystonic posturing, choreoathetosis, ocular nystagmus, and various other ocular motor abnormalities. [1] [6] Almost half of all people have dystonic symptoms prior to experiencing hemiplegia. [4] These symptoms generally begin before 8 months of age. [8]
As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of ACh, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning. Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils).
Hirschsprung's disease (HD or HSCR) is a birth defect in which nerves are missing from parts of the intestine. [1] [3] The most prominent symptom is constipation. [1] Other symptoms may include vomiting, abdominal pain, diarrhea and slow growth. [1] Most children develop signs and symptoms shortly after birth.
Other signs of Lyme disease include fever, chills, headache, fatigue, and a bullseye-shaped rash. Diagnosis mainly takes two things into consideration: the presence of these symptoms and the ...
Individuals symptoms vary in severity and type. Severe, subacute gastrointestinal dysmotility and orthostatic hypotension are the most common symptoms in two-thirds of patients. Symptoms can be severe in some cases and gradually worsen in others. [1] Sympathetic failure manifests itself as orthostatic hypotension and anhidrosis.
The underlying mechanism involves the inhibition of acetylcholinesterase (AChE), leading to the buildup of acetylcholine (ACh) in the body. [2] Diagnosis is typically based on the symptoms and can be confirmed by measuring butyrylcholinesterase activity in the blood. [2] Carbamate poisoning can present similarly. [2]
The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:
Mild symptoms include tachycardia, flushed face, mydriasis and blurred vision, fever, dry mouth and skin, and urinary retention. Early stage of overdose can lead to central nervous system stimulation, for instance, hyperactivity, followed by depression, such as agitation (Anxiety or nervous), delirium , disorientation, hallucinations, seizures ...