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Carbamazepine, sold under the brand name Tegretol among others, is an anticonvulsant medication used in the treatment of epilepsy and neuropathic pain. [ 4 ] [ 1 ] It is used as an adjunctive treatment in schizophrenia along with other medications and as a second-line agent in bipolar disorder .
In the United States, cenobamate is indicated for the treatment of partial-onset seizures in adults. [3]In the European Union, it is indicated for the adjunctive treatment of focal-onset seizures with or without secondary generalization in adults with epilepsy who have not been adequately controlled despite a history of treatment with at least two anti-epileptic medications.
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication. The list is not exhaustive and not all drugs are used regularly in all countries.
Tegretol (carbamazepine) – an anticonvulsant used as a mood stabilizer; Trilafon (perphenazine)- an antipsychotic used to treat schizophrenia; Tranxene, Novo-Clopate (clorazepate) – a benzodiazepine with anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties
Low IC 50 or high pIC 50 values indicate tighter binding (pIC 50 of 8.0 = IC 50 of 10nM, pIC 50 of 9.0 = IC 50 of 1nM, etc.) These are non subtype selective IC 50 values averaged across all GABA A receptor subtypes , so subtype selective compounds with strong binding at one subtype but weak at others will appear unusually weak due to averaging ...
Remacemide, under the trade name Ecovia, was designated an orphan drug for the treatment of Huntington's disease by the FDA in March 2000. [ 1 ] Remacemide was last mentioned in AstraZeneca 's reports on its R&D pipeline in 2000, when it was in Phase III clinical trials for remacemide in the treatment of Huntington's disease and Phase II for ...
A correlation exists between average clinical potency and affinity of the antipsychotics for dopamine receptors. [50] Chlorpromazine tends to have a greater effect at serotonin receptors than at D2 receptors, which is notably the opposite effect of the other typical antipsychotics. Therefore, chlorpromazine's effects on dopamine and serotonin ...
The other group comprises those that are metabolized through glucuronidation, such as lorazepam, oxazepam, and temazepam, and, in general, have few drug interactions. [ 82 ] Many drugs, including oral contraceptives , some antibiotics , antidepressants , and antifungal agents, inhibit cytochrome enzymes in the liver.
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related to: other names for carbamazepine 50 000 mg