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Essential tremor (ET), also called benign tremor, familial tremor, and idiopathic tremor, is a medical condition characterized by involuntary rhythmic contractions and relaxations (oscillations or twitching movements) of certain muscle groups in one or more body parts of unknown cause. [6]
Ulixacaltamide is an investigational new drug developed by Praxis Precision Medicines, designed to treat essential tremor, [1] a common neurological disorder characterized by involuntary rhythmic shaking.
Hence, the drug is theorized to have improved tolerability. [4] [5] [6] PRAX-114 shows antidepressant-like, anxiolytic-like, and, at higher doses, sedative effects in animals. [4] [5] [6] As of March 2023, PRAX-114 is in phase 2/3 clinical trials for major depressive disorder and phase 2 clinical trials for essential tremor.
The drug, called suvecaltamide, was being tested in adults with essential tremor, a condition that affects the nervous system and causes involuntary and rhythmic shaking, affecting about 10 ...
Trihexyphenidyl (THP, benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease.
Primidone, sold under various brand names (including Mysoline), is a barbiturate medication that is used to treat partial and generalized seizures [7] and essential tremors. [8] It is taken by mouth. [7] Its common side effects include sleepiness, poor coordination, nausea, and loss of appetite. [7] Severe side effects may include suicide and ...
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