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  2. Anti-gliadin antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-gliadin_antibodies

    Anti-gliadin antibodies were one of the first serological markers for coeliac disease. Problematic with AGA is the typical sensitivity and specificity was about 85%. Gliadin peptides which are synthesized as the deamidated form have much higher sensitivity and specificity, creating 2 serological tests for CD that approach biopsy diagnostic in ...

  3. Anti-transglutaminase antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-transglutaminase...

    In disease, transglutaminase reacts with gliadin forming a linkage. [21] In forming this bond transglutaminase becomes linked to T-cell epitopes on gliadin. B-cells with surface IgM that react to transglutaminase can present it with bound gliadin peptides to T-cells which stimulate B-cell maturation and proliferation to plasma cells making IgA ...

  4. Gluten immunochemistry - Wikipedia

    en.wikipedia.org/wiki/Gluten_immunochemistry

    Deamidated gliadin peptides are more inflammatory relative to natural peptides. Deamidated gliadin is also found in foods that have added gluten, such as wheat bread, food pastes. The major gluten proteins that are involved in coeliac disease are the α-gliadin isoforms. Alpha gliadin is composed of repeated motifs that, when digested, can be ...

  5. Are doctors overtreating early-stage breast cancer? Is active ...

    www.aol.com/doctors-overtreating-early-stage...

    Cancer is typically treated with surgery, radiation and sometimes chemotherapy. But a new study suggests this standard protocol might not be necessary for a common form of early-stage breast cancer.

  6. Some Early Forms of Breast Cancer May Not Need Treatment ...

    www.aol.com/early-forms-breast-cancer-may...

    Breast cancer is not a single disease but multiple ones, each carrying varying degrees of risk for endangering women’s health. In recent years, many researchers have been focused on DCIS: ductal ...

  7. AI detects woman’s breast cancer after routine screening ...

    www.aol.com/ai-detects-woman-breast-cancer...

    A U.K. woman had her breast cancer detected through AI after a routine mammogram came back as normal. Experts Drs. Nicole Saphier and Harvey Castro discuss the power of AI in cancer care.

  8. Tissue transglutaminase - Wikipedia

    en.wikipedia.org/wiki/Tissue_transglutaminase

    Serology for anti-tTG antibodies has superseded older serological tests (anti-endomysium, anti-gliadin, and anti-reticulin) and has a strong sensitivity (99%) and specificity (>90%) for identifying celiac disease. Modern anti-tTG assays rely on a human recombinant protein as an antigen. [43]

  9. Certain foods may disrupt your body’s fight against cancer ...

    www.aol.com/certain-foods-may-disrupt-body...

    Higher levels of omega-6 fatty acids often found in ultraprocessed foods may interfere with the immune system’s fight against cancer cells, a new study says.