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  2. GABA reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/GABA_reuptake_inhibitor

    A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs). This in turn leads to increased extracellular concentrations of GABA and therefore an increase in GABAergic neurotransmission. [1]

  3. GABA receptor agonist - Wikipedia

    en.wikipedia.org/wiki/GABA_receptor_agonist

    Many commonly used sedative and anxiolytic drugs that affect the GABA receptor complex are not agonists. These drugs act instead as positive allosteric modulators (PAMs) and while they do bind to the GABA receptors, they bind to an allosteric site on the receptor and cannot induce a response from the neuron without an actual agonist being present.

  4. SSRIs: Everything You Need to Know Before Starting Them - AOL

    www.aol.com/ssris-everything-know-starting-them...

    Since SSRI drugs can affect your serotonin levels and, theoretically, improve your mood, they’re often prescribed for anxiety, depression and so many more mental health conditions, as well as ...

  5. Selective serotonin reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Selective_serotonin...

    Post-SSRI sexual dysfunction (PSSD) [63] [64] refers to a set of symptoms reported by some people who have taken SSRIs or other serotonin reuptake-inhibiting (SRI) drugs, in which sexual dysfunction symptoms persist for at least three months [65] [66] [67] after ceasing to take the drug. The status of PSSD as a legitimate and distinct pathology ...

  6. Breakthrough antidepressants with fewer side effects could ...

    www.aol.com/finance/breakthrough-antidepressants...

    GABA: The yin to glutamate’s yang. ... There may be untold other targets for antidepressant drugs. Murrough, for example, is currently conducting research into an anti-seizure drug that, until ...

  7. Reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Reuptake_inhibitor

    Escitalopram, a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant.. Reuptake inhibitors (RIs) are a type of reuptake modulators.It is a drug that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.

  8. How Herbal Supplements Can Interfere with Medications ... - AOL

    www.aol.com/herbal-supplements-interfere...

    How Herbal Supplements Can Interfere with Medications. ... (SSRIs). This is because a few of the compounds within St. John’s Wort also work to inhibit the reuptake of these neurotransmitters ...

  9. GABAA receptor positive allosteric modulator - Wikipedia

    en.wikipedia.org/wiki/GABAA_receptor_positive...

    Unlike GABA A receptor agonists, GABA A PAMs do not bind at the same active site as the γ-aminobutyric acid (GABA) neurotransmitter molecule: they affect the receptor by binding at a different site on the protein. This is called allosteric modulation. In psychopharmacology, GABA A receptor PAMs used as drugs have mainly sedative and anxiolytic ...