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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Albert Sabin, a virologist who publicly disagreed with Salk and his killed vaccine, worked on creating a vaccine with live attenuated vaccines. [5] In January 1956, despite Cold War tensions, Mikhail Chumakov, the director of Moscow's Polio Research Institute, along with his wife virologist Marina Voroshilova, and his colleague Anatoli Smorodentsev, traveled to the U.S. in order to study the ...
There are two kinds of polio vaccine—oral polio vaccine (OPV), which uses weakened poliovirus, and inactivated polio vaccine (IPV), which is injected. OPV is less expensive and easier to administer, and can spread immunity beyond the person vaccinated, creating contact immunity. It has been the predominant vaccine used.
Polio: An American Story by David M. Oshinsky, professor of history at the University of Texas at Austin, documents the polio epidemic in the United States during the 1940s and 1950s and the race to develop a vaccine, which led to 2 different types of polio vaccine: inactivated poliovirus vaccine, developed by a team led by Jonas Salk, and oral poliovirus vaccine, developed by a team led by ...
This is a timeline of the development of prophylactic human vaccines.Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market.
Two vaccines are used throughout the world to combat poliomyelitis.The first, a polio vaccine developed by Jonas Salk, is an inactivated poliovirus vaccine (IPV), consisting of a mixture of three wild, virulent strains of poliovirus, grown in a type of monkey kidney tissue culture (Vero cell line), and made noninfectious by formaldehyde treatment.
There are some purported side effects that happen so rarely it is not proven that they are caused by the vaccine, they include deafness; long-term seizures, coma or lowered consciousness; permanent brain damage; Some side effects of the MMRV vaccine are [2] fever (1 in 6) mild rash (1 in 20) swelling of glands in cheeks or neck (1 in 75)
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