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Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs.These drugs cause an autoimmune response (the body attacks its own cells) producing symptoms similar to those of systemic lupus erythematosus (SLE).
Fixed drug reactions are common and so named because they recur at the same site with each exposure to a particular medication. [1] Medications inducing fixed drug eruptions are usually those taken intermittently.
Pages in category "Drug-induced diseases" The following 18 pages are in this category, out of 18 total. ... Drug-induced lupus erythematosus; Drug-induced ...
E946 Agents primarily affecting skin and mucous membrane ophthalmological otorhinolaryngological and dental drugs causing adverse effects in therapeutic use; E947 Other and unspecified drugs and medicinal substances causing adverse effects in therapeutic use; E948 Bacterial vaccines causing adverse effects in therapeutic use
Ninety-six percent of patients with lupus induced by procainamide will have a positive test for anti-histone antibodies, and 100% of patients whose lupus was induced by penicillamine, isoniazid, or methyldopa will have a positive test for anti-histone antibodies. In 70% of patients with rheumatoid arthritis, Felty's syndrome, Sjogren's syndrome ...
Lupus erythematosus may manifest as systemic disease or in a purely cutaneous form also known as incomplete lupus erythematosus. Lupus has four main types: [citation needed] systemic; discoid; drug-induced; neonatal; Of these, systemic lupus erythematosus (also known as SLE) is the most common and serious form.
There are also a few types of medications, including certain antibiotics as well as seizure, anti-inflammatory and blood pressure treatments, that can trigger drug-induced lupus erythematosus, or ...
Hydroxychloroquine was approved by the FDA for lupus in 1955. [120] Some drugs approved for other diseases are used for SLE 'off-label'. In November 2010, an FDA advisory panel recommended approving belimumab (Benlysta) as a treatment for the pain and flare-ups common in lupus. The drug was approved by the FDA in March 2011. [121] [122]
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