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Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
While Teva sees revenue from generic Revlimid slowing down later this year, it expects to minimize the impact of competition. The drugmaker said liraglutide, a generic of Novo Nordisk's drug ...
The company said sales of Revlimid and another blood cancer drug Pomalyst were also hurt by an increase in patients receiving them at no cost through its patient assistance foundation.
Apremilast is available in the US, but is dispensed only through a network of specialty pharmacies. [21] The estimated wholesale price is US$22,500 for a year of treatment. [24] In Austria, a year of treatment costs health insurances about €11,000 as of 2018. [25] Celgene made Otezla available in the UK in 2015. [26]
Celgene (CELG) receives positive CHMP opinion for label expansions of IMiD medications - Revlimid and Imnovid.
Phase II clinical trials for multiple myeloma and myelofibrosis reported 'promising results'. [ 22 ] [ 23 ] Phase III results showed significant extension of progression-free survival , and overall survival (median 11.9 months vs. 7.8 months; p = 0.0002) in patients taking pomalidomide and dexamethasone vs. dexamethasone alone.
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
In 2012, NATCO Pharma obtained compulsory license to produce a cheaper and generic version of Bayer's anti-cancer medication Nexavar. [ 7 ] In the United States, it launched influenza medication Tamiflu with marketing partner Alvogen , multiple sclerosis treatment drug glatiramer acetate in partnership with Mylan , and hepatitis C drugs under a ...
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