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N-acetylphosphatidylethanolamine-hydrolysing phospholipase D (EC 3.1.4.54, NAPE-PLD, anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, NAPE-hydrolyzing phospholipase D) is an enzyme with systematic name N-acetylphosphatidylethanolamine phosphatidohydrolase. [1] [2] It catalyses the following chemical reaction
N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) is an enzyme that catalyzes the release of N-acylethanolamine (NAE) from N-acyl-phosphatidylethanolamine (NAPE). This is a major part of the process that converts ordinary lipids into chemical signals like anandamide and oleoylethanolamine .
A hydrophobic cavity in NAPE-PLD provides an entryway for the substrate NAPE into the active site, where a binuclear zinc center orchestrates its hydrolysis. Unexpectedly, the structure unveils bile acids bind the membrane enzyme, enhancing dimer assembly and enabling catalysis.
NAPE-PLD may refer to: N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [ wikidata ] N-acyl phosphatidylethanolamine-specific phospholipase D , an enzyme
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Since 2003, the *ist D is the only digital SLR that can control HS wireless P-TTL from its pop-up flash and has many advanced features for professional applications. In 2004 Pentax released the second member in the digital *ist line, the Pentax *ist DS which is the first real consumer model (retailing under US$1,000). What set Pentax D and DS ...
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The *ist DS was a lower-prices follow-on to the Pentax *ist D. In September 2005 the Digital Imaging Websites Association (DIWA), a worldwide organization of collaborating websites, announced that Pentax had received their first DIWA Award for a DSLR camera. The *ist DS model was awarded with a Silver medal for outstanding test results.