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Side effects of HDE specific to men may include gynecomastia (breast development), feminization and demasculinization in general (e.g., reduced body hair, decreased muscle mass and strength, feminine changes in fat mass and distribution, and reduced penile and testicular size), and sexual dysfunction (e.g., reduced libido and erectile dysfunction).
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Side effects of estrogens like estrone include breast tenderness, breast enlargement, headache, nausea, fluid retention, and edema, among others. [5] Estrone is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor , the biological target of estrogens like endogenous estradiol . [ 5 ]
The doctor will then look for the root cause of the high estrogen and suggest appropriate treatment options. Treating Conditions Related To High Estrogen Lifestyle changes can go a long way in ...
Therefore, men are more likely to develop severe symptoms of anxiety and possibly develop an additional depressive disorder due to the lack of treatment intervention.”
Also has a high incidence of psychiatric side effects such as depression, anxiety, and fatigue. [citation needed] Spironolactone (Aldactone): An antimineralocorticoid (aldosterone antagonist) with additional/coincidental antiandrogen activity. Specifically acts as an AR antagonist, weak antigonadotropin, and weak steroidogenesis inhibitor.
As a rule, feminization, a gynoid fat distribution, demasculinization, and impotence are said to occur in virtually or nearly 100% of men treated with high-dose estrogen therapy. [13] [26] Decreased sexual activity has also been reported in men treated with EMP. [1] These side effects are due to high estrogen levels and low testosterone levels.
In men, the side effects of antidepressants result in reduced drive (low libido) or lowered desire, delayed climax, and difficulties with developing and maintaining arousal.
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