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The most dangerous side effect of pyrazinamide is hepatotoxicity, which is dose-related. The old dose for pyrazinamide was 40–70 mg/kg daily and the incidence of drug-induced hepatitis has fallen significantly since the recommended dose has been reduced to 12–30 mg/kg daily. In the standard four-drug regimen (isoniazid, rifampicin ...
Patients at risk of peripheral neuropathy from other causes (diabetes mellitus, alcoholism, renal failure, malnutrition, pregnancy, etc.) should all be given pyridoxine 10 mg daily at the start of treatment. Please refer to the entry on isoniazid for details on other neurological side effects of INH. [citation needed]
It is a fixed dose combination of rifampicin, isoniazid, and pyrazinamide. [1] It is used either by itself or along with other antituberculosis medication. [1] It is taken by mouth. [1] Side effects are those of the underlying medications. [1] These may include poor coordination, loss of appetite, nausea, joint pain, feeling tired, and numbness ...
Starting a new medication for your mental health can be a time full of uncertainty. And there’s a lot of information about antidepressant medications out there.
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[3] [4] Long-term use may cause yellowing of nails. [7] Phenazopyridine should be avoided by people with glucose-6-phosphate dehydrogenase deficiency, [4] [8] [9] [10] because it can cause hemolysis (destruction of red blood cells) due to oxidative stress. [11] It has been reported to cause methemoglobinemia after overdose and even normal doses ...
Isoniazid decreases the metabolism of carbamazepine, thus slowing down its clearance from the body. People taking carbamazepine should have their carbamazepine levels monitored and, if necessary, have their dose adjusted accordingly. [38] It is possible that isoniazid may decrease the serum levels of ketoconazole after long-term treatment.
But some research has noted rare but serious side effects of once-weekly, 2.4-milligram (mg) semaglutide injections, such as pancreatitis, acute kidney injury, gallbladder issues, and thyroid cancer.