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  2. Phenytoin - Wikipedia

    en.wikipedia.org/wiki/Phenytoin

    Phenytoin (PHT), sold under the brand name Dilantin among others, [1] is an anti-seizure medication. [3] ... Blood levels can be measured to determine the proper dose ...

  3. Fosphenytoin - Wikipedia

    en.wikipedia.org/wiki/Fosphenytoin

    Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in 1996.

  4. Trough level - Wikipedia

    en.wikipedia.org/wiki/Trough_level

    In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is ...

  5. Ethosuximide - Wikipedia

    en.wikipedia.org/wiki/Ethosuximide

    Valproates can either decrease or increase the levels of ethosuximide; however, combinations of valproates and ethosuximide had a greater protective index than either drug alone. [14] It may elevate serum phenytoin levels.

  6. Carbamazepine - Wikipedia

    en.wikipedia.org/wiki/Carbamazepine

    Lower levels of carbamazepine are seen when administered with phenobarbital, phenytoin, or primidone, which can result in breakthrough seizure activity. [ 33 ] Valproic acid and valnoctamide both inhibit microsomal epoxide hydrolase (mEH), the enzyme responsible for the breakdown of the active metabolite carbamazepine-10,11-epoxide into ...

  7. Today’s NYT ‘Strands’ Hints, Spangram and Answers for ...

    www.aol.com/today-nyt-strands-hints-spangram...

    Related: The 26 Funniest NYT Connections Game Memes You'll Appreciate if You Do This Daily Word Puzzle. What Are Today’s NYT Strands Hints? Warning: Spoilers ahead!

  8. Nicole Kidman Worked With 19 Female Directors in Eight Years ...

    www.aol.com/nicole-kidman-worked-19-female...

    Nicole Kidman made a vow in 2017 to work with a woman director every 18 months. To say she has made good on that promise would be an understatement. The Oscar winner has teamed up with a women ...

  9. Therapeutic drug monitoring - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_drug_monitoring

    Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood.Its main focus is on drugs with a narrow therapeutic range, i.e. drugs that can easily be under- or overdosed. [1]