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The eclipse period is a variable period starting from HIV exposure in which no existing test can detect HIV. The median duration of the eclipse period in one study was 11.5 days. The window period is the time between HIV exposure and when an antibody or antigen test can detect HIV. The median window period for antibody/antigen testing is 18 days.
This is a timeline of HIV/AIDS, including but not limited to cases before 1980. Pre-1980s See also: Timeline of early HIV/AIDS cases Researchers estimate that some time in the early 20th century, a form of Simian immunodeficiency virus found in chimpanzees (SIVcpz) first entered humans in Central Africa and began circulating in Léopoldville (modern-day Kinshasa) by the 1920s. This gave rise ...
In a clinical study, trained professionals compared HIV test results of OraQuick In-Home HIV Test with results from laboratory testing. The study was conducted on 4,999 participants and found OraQuick testing correctly generated a negative result 4,902 times out of the 4,903 times laboratory testing generated a negative result (99.9%). [ 10 ]
Previous generation tests relied on detecting patient antibodies alone; it takes about 3–4 weeks for the earliest antibodies to be detected. The p24 protein can be detected in a patient's blood as early as 2 weeks after infection, further reducing the window period necessary to accurately detect the HIV status of the patient. [15]
A course of antiretrovirals administered within 48 to 72 hours after exposure to HIV-positive blood or genital secretions is referred to as post-exposure prophylaxis (PEP). [144] The use of the single agent zidovudine reduces the risk of an HIV infection five-fold following a needle-stick injury. [144]
An HIV antibody test usually detects the HIV antibodies within two to eight weeks, but can have a valid negative result for a long as 2 to 6 months after initial infection. Viral load tests can also be used to diagnose HIV infection, especially in children under 18 months born to mothers with HIV, where the presence of maternal antibodies ...
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