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Patients whose epilepsy is uncontrolled by their medication (i.e., it is refractory to treatment) are selected to see if supplementing the medication with the new drug leads to an improvement in seizure control. Any reduction in the frequency of seizures is compared against a placebo. [21]
In epilepsy surgery, a distinction can be made between resective and disconnective procedures. In a resective procedure the area of the brain that causes the seizures is removed. In a disconnective procedure the neural connections in the brain that allow the seizures to spread are disconnected.
Epilepsy affects over 60 million people worldwide, with approximately 30% of patients unresponsive to AEDs. [8] In these patients, surgery is the standard of care, which involves identifying and removing the brain's epileptogenic zone (EZ) from where seizures originate. However, accurately localizing has proven to be a significant research ...
Thus far, in both migraine and epileptic cases of FN, the psychosis that develops is hypothesized to be rooted largely in non limbic structures of the brain, like the amygdala, cerebrum, and olfactory bulb. [9] Both antiepileptic drugs (AEDs) and antimigraine medications do not affect these areas and, therefore, do not affect psychiatric activity.
The pre-surgical evaluation for epilepsy is designed to locate the "epileptic focus" or the "epileptogenic zone" (the location where the epilepsy originates in the brain) and to determine if/how surgery could affect normal brain function. [8]
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This condition is known as photosensitive epilepsy and, in some cases, the seizures can be triggered by activities that are harmless to others, such as watching television or playing video games, or by driving or riding during daylight along a road with spaced trees, thereby simulating the "flashing light" effect. Some people can have a seizure ...
Growing up, I always believed that bad things happened somewhere else, to someone else. That illusion was shattered three times. When I was 17, my father suffered a sudden cardiac arrest and ...