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Alphacoronavirus amsterdamense [1] ( also called Human coronavirus NL63 abbreviated HCoV-NL63) is a species of coronavirus, specifically a Setracovirus from among the Alphacoronavirus genus. It was identified in late 2004 in patients in the Netherlands by Lia van der Hoek and Krzysztof Pyrc [ 2 ] using a novel virus discovery method VIDISCA. [ 3 ]
The most recent COVID-19 vaccine should offer protection against the XEC variant, Russo says. “The most recent version of the vaccine seems to be reasonably well-matched,” he says.
By 2010, in vitro experiments had confirmed that modifications to the spike protein receptor binding domain could enable human infection by several SARS-related coronaviruses. [9] Virologists Rachel Graham and Ralph S. Baric at that time wrote, "that the question of emergence of another pathogenic human coronavirus from bat reservoirs might be ...
HCoV-229E is associated with a range of respiratory symptoms, ranging from the common cold to high-morbidity outcomes such as pneumonia and bronchiolitis.However, such high morbidity outcomes are almost always seen in cases with co-infection with other respiratory pathogens; there is a single published case report to date of a 229E infection that caused acute respiratory distress syndrome ...
Humans Common cold: Human coronavirus OC43 (HCoV‑OC43) 1967 [23] Possibly originated from rodents, then jumped through cattle to humans. [24] Pigs Enteritis: Porcine epidemic diarrhea virus (PEDV) 1971 [25] Infects pigs. Caused outbreaks in 1972 [26] and 1978, [27] 2010, 2013, 2014, and 2015. [28] Dogs Enteritis: Canine coronavirus (CCoV ...
The betacoronaviruses of the greatest clinical importance concerning humans are OC43 and HKU1 (which can cause the common cold) of lineage A, SARS-CoV-1 and SARS-CoV-2 (the causes of SARS and COVID-19 respectively) of lineage B, [2] and MERS-CoV (the cause of MERS) of lineage C. MERS-CoV is the first betacoronavirus belonging to lineage C that ...
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The human coronavirus NL63 shared a common ancestor with a bat coronavirus (ARCoV.2) between 1190 and 1449 CE. [76] The human coronavirus 229E shared a common ancestor with a bat coronavirus (GhanaGrp1 Bt CoV) between 1686 and 1800 CE. [77] More recently, alpaca coronavirus and human coronavirus 229E diverged sometime before 1960. [78]