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Other possible adverse effects regardless of the mode of administration include increased oxalate excretion and kidney stones, increased uric acid excretion, systemic conditioning ("rebound scurvy"), preoxidant effects, iron overload, reduced absorption of vitamin B 12 and copper, increased oxygen demand, and acid erosion of the teeth when ...
Concerns about possible adverse effects are that intravenous high-dose vitamin C leads to a supraphysiological level of vitamin C followed by oxidative degradation to dehydroascorbic acid and hence to oxalate, increasing the risk of oxalate kidney stones and oxalate nephropathy.
Side effects from vitamin overdoses may occur, especially in patients with kidney failure. In very large doses, vitamin C in kidney-failure patients can cause severe side effects such as oxalate deposits in bone and soft tissues and may interfere with the absorption and metabolism of vitamin B 12. The product contains 1 g of vitamin C per ...
A kidney stone is a hard object, which can be as small as a grain of salt or as big as a golf ball, made from chemicals—calcium oxalate, uric acid, struvite, and cystine—found in our urine.
"Pure uric acid stones, for example, may be dissolved by decreasing the acidity or alkalinizing the urine." Medical expulsive therapy Dr. Porter says that certain medications when combined with ...
For forced acid diuresis, ascorbic acid is sometimes used. Ammonium chloride has also been used for forced acid diuresis, but it is a toxic compound. [ 6 ] Usually, however, this technique only produces a slight increase in the renal clearance of the drug.
Proponents of orthomolecular medicine argue that supplements are less likely to cause dangerous side-effects or harm, since they are normally present in the body. [5] Some vitamins are toxic in high doses [ 70 ] and nearly all (with the possible exception of Vitamin C [ 85 ] ) will cause adverse effects given high levels of overdosing for ...
As the sodium salt of ascorbic acid, it is known as a mineral ascorbate. It has not been demonstrated to be more bioavailable than any other form of vitamin C supplement. [2] Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).
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