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  2. DaT scan - Wikipedia

    en.wikipedia.org/wiki/DAT_Scan

    DaT Scan (DaT scan or Dopamine Transporter Scan) commonly refers to a diagnostic method, based on SPECT imaging, to investigate if there is a loss of dopaminergic neurons in striatum. The term may also refer to a brand name of Ioflupane (123I) tracer used for the study.

  3. Dihydroergocryptine - Wikipedia

    en.wikipedia.org/wiki/Dihydroergocryptine

    Acute side-effects usually accompany the beginning of treatment but tend to decrease as the patient develops increased tolerance to the drug. [14] In randomized, double-blinded trials, individuals on different dopamine agonists, including dihydroergocryptine, did not differ in discontinuation rate associated with adverse events.

  4. Aromatic L-amino acid decarboxylase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatic_L-amino_acid_de...

    Peripherally selective DDCIs incapable of crossing the protective blood–brain barrier (BBB) are used in augmentation of L-DOPA (levodopa) in the treatment of Parkinson's disease (PD) to block the conversion of L-DOPA into dopamine outside the brain, for the purpose of reducing adverse side effects. [3]

  5. Ioflupane (123I) - Wikipedia

    en.wikipedia.org/wiki/Ioflupane_(123I)

    Ioflupane has a high binding affinity for presynaptic dopamine transporters in the brains of mammals, in particular the striatal region of the brain. A feature of Parkinson's disease is a marked reduction in dopaminergic neurons in the striatal region. By introducing an agent that binds to the dopamine transporters a quantitative measure and ...

  6. Dopaminergic - Wikipedia

    en.wikipedia.org/wiki/Dopaminergic

    Aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitors including benserazide, carbidopa, and methyldopa, which are used in the treatment of Parkinson's disease in augmentation of L-DOPA to block the peripheral conversion of dopamine, thereby inhibiting undesirable side-effects, and as sympatholytic or antihypertensive agents.

  7. Dopamine transporter - Wikipedia

    en.wikipedia.org/wiki/Dopamine_transporter

    6531 13162 Ensembl ENSG00000142319 ENSG00000276996 ENSMUSG00000021609 UniProt Q01959 Q61327 RefSeq (mRNA) NM_001044 NM_010020 RefSeq (protein) NP_001035 NP_034150 Location (UCSC) Chr 5: 1.39 – 1.45 Mb Chr 13: 73.68 – 73.73 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded ...

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