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Discoid lupus erythematosus is the most common type of chronic cutaneous lupus (CCLE), an autoimmune skin condition on the lupus erythematosus spectrum of illnesses. [1] [2] It presents with red, painful, inflamed and coin-shaped patches of skin with a scaly and crusty appearance, most often on the scalp, cheeks, and ears.
A breakthrough was made in 1948 with the discovery of the LE cell (the lupus erythematosus cell—a misnomer, as it occurs with other diseases as well). Discovered by a team of researchers at the Mayo Clinic, they discovered that the white blood cells contained the nucleus of another cell that was pushing against the white's cell proper nucleus.
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
Rashes or sores on the scalp, which can be a symptom of lupus. Discoid lupus erythematosus (DLE) is a type of cutaneous lupus that leads to round skin lesions. These lesions can be more prone to ...
Discoid lupus erythematosus: Skin ANA, Anti-dsDNA, Anti-Sm Confirmed Part of SLE prevalence (20-150 per 100,000) [11] Epidermolysis bullosa acquisita: Skin Anti-type VII collagen Confirmed Extremely rare [12] Erythema nodosum: Skin None specific Possible Not well established [13] Gestational pemphigoid: Skin Anti-BP180, Anti-BP230 Confirmed ...
Discoid lupus. Round, coin-shaped sores on the scalp can be caused by discoid lupus. This is an autoimmune disease with no known cause but can run in families. The lesions caused by discoid lupus ...
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]
The Centers for Disease Control and Prevention estimates that more than 200,000 people in the U.S. have lupus, though the Lupus Foundation of America puts the total much higher: roughly 1.5 ...
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