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The gastrocolic reflex or gastrocolic response is a physiological reflex that controls the motility, or peristalsis, of the gastrointestinal tract following a meal. It involves an increase in motility of the colon consisting primarily of giant migrating contractions, in response to stretch in the stomach following ingestion and byproducts of digestion entering the small intestine. [1]
The enterogastric reflex is one of the three extrinsic reflexes of the gastrointestinal tract, the other two being the gastroileal reflex and the gastrocolic reflex. [1] The enterogastric reflex is stimulated by duodenal distension. [2] It can also be stimulated by a pH of 3-4 in the duodenum and by a pH of 1.5 in the stomach.
When this occurs, the reflex is called a short reflex. [4] Although this may be the case in several situations, the ENS can also work in conjunction with the CNS; vagal afferents from the viscera are received by the medulla, efferents are affected by the vagus nerve. When this occurs, the reflex is called vagovagal reflex.
Pro tip: Oatmeal is your friend. Nuts, not so much.
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"We're just trying to break those reflex arc pathways to stop the hiccups," says Adamian. Here are several popular, accessible, low-risk methods you can try to get rid of hiccups. Hold your breath
It also decreases colonic mass movements and suppresses the gastrocolic reflex. [36] Loperamide's circulation in the bloodstream is limited in two ways. Efflux by P-glycoprotein in the intestinal wall reduces the passage of loperamide, and the fraction of drug crossing is then further reduced through first-pass metabolism by the liver.
Instead, general contractions called mass action contractions occur one to three times per day in the large intestine, propelling the chyme (now feces) toward the rectum. Mass movements often tend to be triggered by meals, as the presence of chyme in the stomach and duodenum prompts them (gastrocolic reflex).