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A drug combination chart designed for harm reduction by TripSit [1] Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals.
Cocaine is the second most popular illegal recreational drug in the United States behind cannabis, [17] and the U.S. is the world's largest consumer of cocaine. [ 18 ] In 2020, the state of Oregon became the first U.S. state to decriminalize cocaine.
Heroin, also known as diacetylmorphine and diamorphine among other names, [1] is a morphinan opioid substance synthesized from the dried latex of the opium poppy; it is mainly used as a recreational drug for its euphoric effects.
It also maintains List I of chemicals and List II of chemicals, which contain chemicals that are used to manufacture the controlled substances/illicit drugs. The list is designated within the Controlled Substances Act [ 1 ] but can be modified by the U.S. Attorney General as illegal manufacturing practices change.
Drug possession is the crime of having one or more illegal drugs in one's possession, either for personal use, distribution, sale or otherwise. Illegal drugs fall into different categories and sentences vary depending on the amount, type of drug, circumstances, and jurisdiction.
These drugs are often called "illegal drugs" but generally what is illegal is their unlicensed production, distribution, and possession. These drugs are also called "controlled substances". Even for simple possession, legal punishment can be quite severe (including the death penalty in some countries). Laws vary across countries, and even ...
Cocaine is the second most popular illegal recreational drug in the United States (behind cannabis) [163] and the U.S. is the world's largest consumer of cocaine. [164] Its users span over different ages, races, and professions.
[17] [159] [160] [161] The drug also interacts with α 2-adrenergic receptors, with the sigma σ 1 and σ 2 receptors, and with the imidazoline I 1 receptor. [17] [141] [142] [143] It is thought that agonism of the serotonin 5-HT 2A receptor by MDMA may mediate the weak psychedelic effects of the drug in humans.