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The main issue with anticoagulation in pregnancy is that warfarin, the most commonly used anticoagulant in chronic administration, is known to have teratogenic effects on the fetus if administered in early pregnancy. [11] [12] Still, there seems to be no teratogenic effect of warfarin before six weeks of gestation. [13]
The use of a single millimeter cutoff (such as 2.5 or 3.0 mm) is inappropriate because nuchal translucency measurements normally increases with gestational age (by approximately 15% to 20% per gestational week from 10 to 13 weeks). [10] At 12 weeks of gestational age, an "average" nuchal thickness of 2.18mm has been observed; however, up to 13% ...
[3] [10] Blood pressure is defined as high when it is greater than 140 mmHg systolic or 90 mmHg diastolic at two separate times, more than four hours apart in a woman after twenty weeks of pregnancy. [3] Pre-eclampsia is routinely screened during prenatal care. [15] [16]
Weeks 14 – 22 Less invasive Blood draw ~1–2 weeks Maternal hormone levels, risk of gestational hypertension and preeclampsia, chromosome abnormalities, neural tube defects Very low risk, however there is the potential for bruising, pain, nerve damage, fainting, haematoma, bacterial infection, and bloodborne pathogen exposure.
The effect of pregnancy on platelet count is unclear, with some studies demonstrating a mild decline in platelet count and other studies that show no effect. [24] The white blood cell count increases with occasional appearance of myelocytes or metamyelocytes in the blood. [24] During labor, there is a rise in leukocyte count.
A pregnancy test is used to determine whether a female is pregnant or not. The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. [1] Testing blood for hCG results in the earliest detection of pregnancy. [2]
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