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  2. Ferroportin - Wikipedia

    en.wikipedia.org/wiki/Ferroportin

    53945 Ensembl ENSG00000138449 ENSMUSG00000025993 UniProt Q9NP59 Q9JHI9 RefSeq (mRNA) NM_014585 NM_016917 RefSeq (protein) NP_055400 NP_058613 Location (UCSC) Chr 2: 189.56 – 189.58 Mb Chr 1: 45.95 – 45.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein ...

  3. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.

  4. Hemochromatosis type 4 - Wikipedia

    en.wikipedia.org/wiki/Hemochromatosis_type_4

    Hemochromatosis type 4 is a hereditary iron overload disorder that affects ferroportin, an iron transport protein needed to export iron from cells into circulation. [1] Although the disease is rare, it is found throughout the world and affects people from various ethnic groups.

  5. Hereditary haemochromatosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_haemochromatosis

    There are five types of hereditary hemochromatosis: type 1, 2 (2A, 2B), 3, 4 [9] and 5, [10] all caused by mutated genes. Hereditary hemochromatosis type 1 is the most frequent, and uniquely related to the HFE gene. It is most common among those of Northern European ancestry, in particular those of Celtic descent. [11]

  6. 15 Celebrities Who Were Caught In Scandalous Affairs In 2024

    www.aol.com/15-celebrities-got-caught-cheating...

    Image credits: Bored Panda #2 Dave Grohl Fathered A Baby Girl Outside Of His Marriage. Lead singer of the Foo Fighters Dave Grohl isn’t trying to hide his truth. Back in September, the musician ...

  7. Human iron metabolism - Wikipedia

    en.wikipedia.org/wiki/Human_iron_metabolism

    In such cases the iron stores of an adult may reach 50 grams (10 times normal total body iron) or more. The most common diseases of iron overload are hereditary hemochromatosis (HH), caused by mutations in the HFE gene, and the more severe disease juvenile hemochromatosis (JH), caused by mutations in either hemojuvelin (HJV) [46] or hepcidin ...

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  9. Juvenile hemochromatosis - Wikipedia

    en.wikipedia.org/wiki/Juvenile_hemochromatosis

    The presence of hemochromatosis may be discovered incidentally on blood testing, or a diagnosis suspected based on symptoms may be supported or ruled out by blood testing. Elevated serum ferritin , an indicator of blood iron levels, and transferrin saturation , which is involved with absorption of iron from the gut, are very common.

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